ACTIVE IMMUNIZATION OF GUINEA PIGS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS I. QUAI~TITATIW EXPERIMENTS WITH VARIOUS PREPARATIONS OF AcTIvE VIRUS
نویسنده
چکیده
The object of this paper is to describe attempts at determining the minimal quantity of the virus of equine encephMomyelitis needed for producing resistance to experimental infection of guinea pigs by way of the nose, skin, and brain. With this known, a basis has been constructed for comparing the immunizing capacity of virus preparations. The Eastern and Western strains were employed in this study in three forms: adsorbed on alumina gel; precipitated by tannin; and chemically untreated, merely passaged through a series of mice.
منابع مشابه
Active Immunication of Guinea Pigs with the Virus of Equine Encephalomyelitis
Active Eastern or Western equine encephalomyelitis virus in three forms,-chemically untreated but simply passaged through series of mice; adsorbed on alumina Gel C, and precipitated by tannin,-yielded practically the same results when employed for the immunization of guinea pigs. The virus is not inactivated by the process of adsorption or precipitation : guinea pigs and mice inoculated in the ...
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